From 1961 to 1966, Van Dyke starred in the CBS sitcom The Dick Van Dyke Show, in which he portrayed a comedy writer named Rob Petrie. Originally the show was supposed to have Carl Reiner as the lead but CBS insisted on recasting and Reiner chose Van Dyke to replace him in the role. Complementing Van Dyke was a veteran cast of comic actors including Rose Marie, Morey Amsterdam, Jerry Paris, Ann Morgan Guilbert, Richard Deacon, and Carl Reiner (as Alan Brady), as well as 23-year-old Mary Tyler Moore, who played Rob's wife Laura Petrie. Van Dyke won three Emmy Awards as Outstanding Lead Actor in a Comedy Series, and the series received four Emmy Awards as Outstanding Comedy Series.
Van Dyke left high school in 1944, his senior year, intending to join the United States Army Air Forces for pilot training during World War II. Denied enlistment several times for being underweight, he was eventually accepted for service as a radio announcer before transferring to the Special Services and entertaining troops in the continental United States. He received his high school diploma in 2004 at the age of 78.