He first gained recognition on radio and Broadway, then he became known for his role as Rob Petrie on the CBS television sitcom The Dick Van Dyke Show, which ran from 1961 to 1966. He also gained significant popularity for roles in the musical films Bye Bye Birdie (1963), Mary Poppins (1964), Chitty Chitty Bang Bang (1968), and Mary Poppins Returns (2018). His other prominent film appearances include roles in The Comic (1969), Dick Tracy (1990), Curious George (2006), Night at the Museum (2006), and Night at the Museum: Secret of the Tomb (2014). Other prominent TV roles include the leads in The New Dick Van Dyke Show (1971–74), Diagnosis: Murder (1993–2001), and Murder 101 (2006–08) which both co-starred his son Barry.
I was an alcoholic for about twenty-five years. In the Fifties and Sixties, everybody had their martini, everybody smoked incessantly. The funny thing is that all through my twenties and early thirties I didn't drink at all. Then we moved to a neighborhood full of young families with the same age kids and everyone drank heavily, there were big parties every night. I would go to work with terrible hangovers which if you're dancing is really hard. I was in deep trouble, you get suicidal and think you just can't go on. I had suicidal feelings, it was just terrible. But then suddenly, like a blessing, the drink started not to taste good. I would feel a little dizzy and a little nauseous and I wasn't getting the click. Today I wouldn't want a drink for anything. But I do occasionally think of taking a nice drag. I've been on this gum for ten years and it's just as addictive but at least it's not hurting my lungs. (2013)
In 1892 Émile Bernard organised a small solo show of Van Gogh's paintings in Paris, and Julien Tanguy exhibited his Van Gogh paintings with several consigned from Johanna van Gogh-Bonger. In April 1894 the Durand-Rue Gallery in Paris agreed to take 10 paintings on consignment from Van Gogh's estate. In 1896, the Fauvist painter Henri Matisse, then an unknown art student, visited John Peter Russell on Belle Île off Brittany. Russell had been a close friend of Van Gogh; he introduced Matisse to the Dutchman's work, and gave him a Van Gogh drawing. Influenced by Van Gogh, Matisse abandoned his earth-coloured palette for bright colours.