There have been numerous debates as to the nature of Van Gogh's illness and its effect on his work, and many retrospective diagnoses have been proposed. The consensus is that Van Gogh had an episodic condition with periods of normal functioning. Perry was the first to suggest bipolar disorder in 1947, and this has been supported by the psychiatrists Hemphill and Blumer. Biochemist Wilfred Arnold has countered that the symptoms are more consistent with acute intermittent porphyria, noting that the popular link between bipolar disorder and creativity might be spurious. Temporal lobe epilepsy with bouts of depression has also been suggested. Whatever the diagnosis, his condition was likely worsened by malnutrition, overwork, insomnia and alcohol.
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In April 1876 he returned to England to take unpaid work as a supply teacher in a small boarding school in Ramsgate. When the proprietor moved to Isleworth in Middlesex, Van Gogh went with him. The arrangement did not work out and he left to become a Methodist minister's assistant. His parents had meanwhile moved to Etten; in 1876 he returned home at Christmas for six months and took work at a bookshop in Dordrecht. He was unhappy in the position and spent his time doodling or translating passages from the Bible into English, French and German. He immersed himself in religion, and became increasingly pious and monastic. According to his flatmate of the time, Paulus van Görlitz, Van Gogh ate frugally, avoiding meat.
Between 1885 and his death in 1890, Van Gogh appears to have been building an oeuvre, a collection that reflected his personal vision, and could be commercially successful. He was influenced by Blanc's definition of style, that a true painting required optimal use of colour, perspective and brushstrokes. Van Gogh applied the word "purposeful" to paintings he thought he had mastered, as opposed to those he thought of as studies. He painted many series of studies; most of which were still lifes, many executed as colour experiments or as gifts to friends. The work in Arles contributed considerably to his oeuvre: those he thought the most important from that time were The Sower, Night Cafe, Memory of the Garden in Etten and Starry Night. With their broad brushstrokes, inventive perspectives, colours, contours and designs, these paintings represent the style he sought.
Van Gogh's stylistic developments are usually linked to the periods he spent living in different places across Europe. He was inclined to immerse himself in local cultures and lighting conditions, although he maintained a highly individual visual outlook throughout. His evolution as an artist was slow, and he was aware of his painterly limitations. He moved home often, perhaps to expose himself to new visual stimuli, and through exposure develop his technical skill. Art historian Melissa McQuillan believes the moves also reflect later stylistic changes, and that Van Gogh used the moves to avoid conflict, and as a coping mechanism for when the idealistic artist was faced with the realities of his then current situation.
Van Dyke left high school in 1944, his senior year, intending to join the United States Army Air Forces for pilot training during World War II. Denied enlistment several times for being underweight, he was eventually accepted for service as a radio announcer before transferring to the Special Services and entertaining troops in the continental United States. He received his high school diploma in 2004 at the age of 78.